武汉多普乐生物医药有限公司
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钱小如
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2881924056
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(±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid,分子式 C14H18O4分子量250.29Beilstein号 1384050MDL号 MFCD00006846
Trolox is an antioxidant derived from water-soluble vitamin E, with oxygen quenching activity. The activity of Trolox ranges between ferulic acid and p-coumaric acid. Studies show that lipid peroxidation, cytotoxicity, and apoptosis induced by cytochrome P450 2E1 in Hep G2 cells is blocked in the presence of Trolox. It has been observed that Trolox can quench free radicals and inhibit methylmercury (MeHg)-induced reactive oxygen species (ROS) generation in C6 glial cells. In addition, Trolox has demonstrated the ability to reduce cytotoxicity of Microcystis aerμginosa and microcystin-LR in Artemia franciscana nauplii. ()-6-hydroxy -2,5,7,8- tetramethylchroman -2- carboxylic acid (Trolox) exhibits free radical scavenging and antioxidant activities.
An antioxidant derived from water-soluble vitamin E ()-6- hydroxy -2,5,7,8- tetramethylchroman -2- carboxylic acid (Trolox) has been used in the equivalent antioxidant test (TEAC) of 6-hydroxy -2,5,7,8- tetramethylchroman -2- carboxylic acid to determine different fruits.
危害声明 | H302, |
警示性声明 | P501,P264,P270, |
RTECS | DJ2273000 |
WGK | 2 |
产品名称 | 奎诺二甲基丙烯酸酯 |
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产品名称 | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid |
产品英文名称 | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid |
别名 | 水溶性维生素E;6-羟基-2,5,7,8-四甲基苯并二氢吡喃-2-甲酸,(±)-6-羟基-2,5,7,8-四甲基色满-2-羧酸 |
英文别名 | Trolox;6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid |
CAS编号 | 53188-07-1 |
分子式 | C14H18O4 |
分子量 | 250.29 |
PubChem CID | 40634 |
MDL号 | MFCD00006846 |
Beilstein | 1384050 |
Reaxys-RN | 5052542 |
规格或纯度 | 98% |
应用 | An antioxidant derived from water-soluble vitamin E (±)-6-羟基-2,5,7,8-四甲基色满-2-羧酸(Trolox)已用于6-羟基-2,5,7,8-四甲基色满-2-羧酸等效抗氧化检测(TEAC)以确定不同水果物种的总抗氧化能力 |
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生化机理 | 抗氧化剂维生素E衍生物。表现出脂质过氧化,DPPH°清除和HO°清除活性。经常用作抗氧化剂标准。具有细胞渗透性和水溶性。 |
熔点 | 187-189 °C |
敏感性 | 空气敏感 |
溶解性 | Soluble in 100% ethanol (25 mg/ml), methanol, water(slightly), DMSO (~20 mg/ml), DMF (~20 mg/ml), and PBS( pH7.2) (~3 mg/ml). |
储存温度 | 2-8°C储存,充氩, |
运输条件 | 冰袋运输, |
品牌 | 多普乐 |